NASDAQ · Genomics · World No.1 DNA sequencing

Illumina

The No.1 in DNA sequencing. It supplies sequencers and consumables to research, pharma and diagnostics, with sequencing 92% of revenue. Q4 revenue $1.16B, FCF $931M. DRAGEN hardware acceleration, cloud analytics (ICA) and BioInsight underpin AI drug discovery. The picks-and-shovels layer that makes techbio data.

ILMN Updated Jul 12, 2026 4 AI consumers· 1 recurring

Per the valuechain.wiki graph, Illumina is directly linked to 3 companies (2 supply, 1 revenue relationships) and reaches 66 companies within two hops; the links are backed by 7 dated sources, 2 of them primary filings (as of 2026-07-12).

Annual return · 2026-07-10'21+2.8%'22-46.9%'23-31.1%'24-1.3%'25-1.8%YTD+45%
Money inResearch · pharma · diagnostics (sequencing · consumables)Revenue $4.3BBio-AI · data (BioInsight · ICA)Tempus AI
IlluminaQ4 2025 revenue $1.16B, FCF $931M
Money outNVIDIAAmazonSemiconductors · devices · components (undisclosed)R&D & capacity expansion (undisclosed)

Financials & Segments

  • Total revenue · Q4 2025 revenue $1.16B, FCF $931M
  • Customer concentration · Sequencing 92%; Billion Cell Atlas.
  • Segments · Sequencing 92% · Data/services

Revenue from

  • Research · pharma · diagnostics (sequencing · consumables) High confidence· Revenue $4.3B · FY2025 · FY2025 revenue (-0.7%); 2026 guidance $4.5-4.6B
    Supplies sequencers and consumables to research, pharma and diagnostics (sequencing 92% of revenue) — the core revenue source where the installed base drives recurring consumable demand.
    Mentions EN consensus (via MarketBeat) Published Jun 1, 2026: Illumina analyst Hold, consensus target ~$124 (2026)
    Confirms EN SEC EDGAR Published Feb 1, 2026: Illumina FY2025 10-K
    Confirms EN Illumina Published Jan 1, 2026: Illumina Billion Cell Atlas accelerates AI and drug discovery
    Mentions KO PharmNews Published May 16, 2023: Illumina completes certification of high-throughput IVD sequencer NovaSeq 6000Dx
  • Bio-AI · data (BioInsight · ICA) Medium confidence
    AI drug-discovery data via BioInsight and cloud analytics.
    Confirms EN Illumina Published Jan 1, 2026: Illumina Billion Cell Atlas accelerates AI and drug discovery
  • Tempus AI Medium confidence
    Supplies sequencers and consumables to precision-oncology diagnostics firm Tempus — a relationship where rising diagnostic throughput drives recurring consumable revenue.
    Confirms EN Tempus Published Feb 24, 2026: Tempus FY2025 results ($1.27B, +83%)

Pays to

  • NVIDIA High confidence
    Accelerates its DRAGEN secondary-analysis pipeline on NVIDIA GPUs and integrates NVIDIA BioNeMo/RAPIDS/MONAI generative genomics AI (Jan 2025 collaboration).
    Confirms EN Illumina Published Jan 13, 2025: Illumina and NVIDIA collaborate to decode biology
  • Amazon High confidence
    Runs Illumina Connected Analytics and BaseSpace on AWS infrastructure (S3, Glacier), storing and computing petabyte-scale genomic data.
    Confirms EN Illumina Published Jun 1, 2024: Illumina AWS partnership
  • Semiconductors · devices · components (undisclosed) Low confidence
    Semiconductors, optics and instrument parts for sequencers.
    Confirms EN SEC EDGAR Published Feb 1, 2026: Illumina FY2025 10-K
  • R&D & capacity expansion (undisclosed) Low confidence
    R&D and manufacturing capacity.
    Confirms EN SEC EDGAR Published Feb 1, 2026: Illumina FY2025 10-K

Value-chain ripple (2 tiers)

Following node-to-node links up to 2 tiers; each firm is shown once, at its nearest tier.

CompanyChain'21'22'23'24'25YTD
Tempus AIlead1····+74.9-1.4
Illuminanode+2.8-46.9-31.1-1.3-1.8+45
NVIDIAbenef1+125.5-50.3+239+171.2+38.9+13.3
Amazonbenef1+2.4-49.6+80.9+44.4+5.2+6.3
SanDiskbenef2·····+707.1
Kioxiabenef2····+1082.1+260.5
Micron Technologybenef2+24.2-45.9+71.9-1+240.2+243.3
Seagate Technologybenef2+87.5-51.4+69.1+4.1+225.3+231.4
Murata Manufacturingbenef2-14-11.7+24.7-16.5+29.9+217.4
Nan Ya PCBbenef2+110.6-46.7-0.5-38.3+188.2+213.4
Marvellbenef2+84.6-57.5+63.7+83.8-22.8+177.8
ASE Technologybenef2+38.3-12.8+60.9+10.1+65.6+167.6
Nebius Groupbenef2····+202.2+162.4
Astera Labsbenef2····+25.6+148.2
Ibidenbenef2+30.4-19.6+51.6-38.6+261+147.1
SK hynixbenef2-0.4-25.6+53.9+48.6+361.1+140.3
Unimicronbenef2+133.5-30.2+35.2-19.7+175.7+131.6
Corningbenef2+5.9-11.6-1.2+60.6+87.8+118.8
Lumentumbenef2+11.6-50.7+0.5+60.1+339.1+117.6
Cienabenef2+45.6-33.8-11.7+88.4+175.8+97
Credo Technologybenef2··+46.3+245.2+114.1+79.2
Samsung Electronicsbenef2-9-14.2+20.9-26.4+212.9+77.9
onsemibenef2+107.5-8.2+33.9-24.5-14.1+77.2
Coherentbenef2-10-48.6+24+117.6+94.8+75.8
Eoptolinkbenef2-10.1-27.7+136.6+197+368.8+74.9
InnoLightbenef2-30.7-18.3+253.7+12+468.1+68.8
GE Vernovabenef2····+99+67.3
Caterpillarbenef2+16+18.6+25.9+24.7+60.3+67
Keysight Technologiesbenef2+56.3-17.2-7+1+26.5+58.5
Delta Electronicsbenef2-3.4+10.4-0.3+59.2+183.8+54.9
Monolithic Powerbenef2+35.5-27.8+79.8-5.6+54.5+49.8
Analog Devicesbenef2+21-4.9+23.4+8.8+29.8+46.7
Wiwynnbenef2+24.7-22.3+206.4+3.5+64.4+45.1
Jabilbenef2+66.4-2.5+87.4+13.3+58.7+44.9
TSMCbenef2+12.1-36.7+42.3+92.6+55.9+43.6
Arista Networksbenef2+97.9-15.6+94.1+87.7+18.5+42.7
Alchip Technologiesbenef2+14.3-8.7+365.1-18.9+0.8+34.7
Quanta Computerbenef2+22.2-12.8+254.5+12.7+8.9+33.4
Cumminsbenef2-1.7+14.1+1.7+48.9+49.4+33.3
Globalstarbenef2+241.2+14.7+45.9+6.7+96.6+31.2
Eatonbenef2+46.7-7.2+56.2+39.5-2.8+28.6
ABBbenef2+23.9+7.3+18.9+39+36.1+27.2
Pegatronbenef2-5.9+0.6+35.3+21.2-23.8+24
Celesticabenef2+37.9+1.3+159.8+215.2+220.3+21.7
Luxshare Precisionbenef2-11.9-30.2-21.2+58.8+29.3+20.6
Digital Realtybenef2+30.7-41+39.9+35.9-10.1+18.2
Amphenolbenef2+34.9-12+31.5+41.3+96.1+18.1
Wistronbenef2+7.9+9.7+272.7-1.6+22.7+14.8
Schneider Electricbenef2+25.9+1.6+25.8+36.1+0.5+13
Foxconn (Hon Hai)benef2-5.1+2.8+7.8+80.1+26.9+10.9
Exelonbenef2+41.5+8.3-14+9.2+20+9.3
King Yuan Electronics (KYEC)benef2+26.7-7.7+132.4+38.6+171+4.2
Procter & Gamblebenef2+20.5-5-0.9+17.3-12.3+4.1
Talen Energybenef2···+214.8+86.1+2.9
Vistrabenef2+19.6+5.1+70.7+261.5+17.7-1.3
BlackRockbenef2+29.4-20.4+17.9+29.3+6.6-2.1
IonQbenef2·-79.3+259.1+237.1+7.4-4.5
Amorepacificbenef2-30.1-5.7-18.4+9.9+8.2-10.5
TE Connectivitybenef2+35.1-27.7+24.6+3.5+61.1-11.3
Recursion Pharmaceuticalsbenef2·-55+27.9-31.4-39.5-13
Quantum Computing Incbenef2-75.8-55.7-39.5+1712.7-38-15.6
D-Wave Quantumbenef2·-85.3-38.9+854.5+211.3-23.2
Nikebenef2+18.7-29-6-29.1-13.8-29.3
BYD Electronicsbenef2-56.1+16-0.4+60.6-19.4-34.4

YTD as of 2026-07-10 · source: Yahoo Finance

The thesis is a 'picks-and-shovels' monopoly that makes genomic data. As the world No.1 in DNA sequencing, sequencers and consumables are 92% of revenue in a razor-and-blade model: once a sequencer is installed, consumables (reagents, flow cells) become recurring revenue, so the installed base is recurring cash flow (Q4 2025 revenue $1.16B, FCF $931M). It also accelerates DRAGEN secondary analysis on NVIDIA GPUs, runs petabyte-scale genomic data on AWS, and via BioInsight and ICA feeds data to AI drug-discovery and diagnostics demand (Tempus and others), broadening into the upstream infrastructure of techbio. Risks are that consumable demand tracks research/pharma funding cycles and slows first in budget cuts, and that low-cost sequencing entrants pressure share and margins.

Analysis generated from returns as of 2026-07-09

Analyst ratings

Consensus: Buy 2 · Hold 0 · Sell 1 · Avg. target $182 · Price $190.2 (07-10) · Upside -4%

BrokerRatingTargetPublished
Evercore ISIOutperform$200Jul 6, 2026Report
Piper SandlerOverweight$200Jul 1, 2026Report
BarclaysUnderweight$145Jun 24, 2026Report

Evercore ISI, Piper Sandler and Guggenheim all lifted targets to $200 in June-July 2026 on clinical demand recovery, while Barclays stays Underweight, leaving consensus near Hold.

Analyses covering this node


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