NASDAQ · Drug-discovery software · Physics-based AI simulation

Schrodinger

A leader in drug-discovery software that fuses physics-based molecular simulation with machine learning: subscription software licensing to pharma (software $200M, ACV $198M) is the stable core, while its own drug pipeline is the upside option. The quality of 2025 revenue of $256M (+23%) lies in large pharma adopting the platform — as in the Novartis multi-target license worth up to $2.4B ($150M upfront). But a cost base that runs simulation on AWS compute and NVIDIA GPUs, plus losses from the in-house pipeline, weigh on profit — so the watch point is the balance between software-subscription growth and pipeline milestones.

SDGR Updated Jul 12, 2026 2 AI consumers· 1 recurring

Per the valuechain.wiki graph, Schrodinger is directly linked to 2 companies (2 supply, 0 revenue relationships) and reaches 37 companies within two hops; the links are backed by 5 dated sources, 1 of them primary filings (as of 2026-07-12).

Annual return · 2026-07-10'21-56%'22-46.3%'23+91.5%'24-46.1%'25-7.3%YTD-7.8%
Money inPharma (physics-based drug discovery SW licensing)Drug discovery collaboration · in-house pipeline
Schrodinger2025 revenue $256M
Money outAmazonNVIDIAR&D & personnel (undisclosed)

Financials & Segments

  • Total revenue · 2025 revenue $256M (+23%)
  • Customer concentration · Software ACV $198M; pharma licensing.
  • Segments · Software licensing ($200M) · Drug discovery/pipeline

Revenue from

  • Pharma (physics-based drug discovery SW licensing) High confidence
    Physics-based simulation software licensing to pharma (software $200M, ACV $198M).
    Confirms EN Schrodinger Published Feb 25, 2026: Schrodinger FY2025 results ($256M, SW $200M)
    Confirms EN Business Wire Published Nov 5, 2025: Schrodinger Q3 2025 results
    Confirms KO BioSpectator Published Nov 15, 2024: Novartis strikes $2.4B non-oncology drug discovery pact with Schrodinger
    Confirms EN Schrodinger Published Nov 12, 2024: Schrödinger Announces Multi-Target Collaboration and Expanded Software Licensing Agreement with Novartis
  • Drug discovery collaboration · in-house pipeline Medium confidence
    Collaboration and own-pipeline milestones — large upside on success, but trial costs drive losses.
    Confirms EN StockTitan Published Feb 25, 2026: Schrodinger 2025 revenue $256M, narrowed loss

Pays to

  • Amazon Medium confidence
    Runs large-scale molecular simulation on AWS cloud — compute is the key upstream cost of revenue.
    Confirms EN Business Wire Published Nov 5, 2025: Schrodinger Q3 2025 results
  • NVIDIA Medium confidence
    NVIDIA for GPU-accelerated free-energy (FEP) calculations — the upstream that governs simulation accuracy and speed.
    Confirms EN StockTitan Published Feb 25, 2026: Schrodinger 2025 revenue $256M, narrowed loss
  • R&D & personnel (undisclosed) Low confidence
    R&D and scientist headcount.
    Confirms EN Schrodinger Published Feb 25, 2026: Schrodinger FY2025 results ($256M, SW $200M)

Value-chain ripple (2 tiers)

Following node-to-node links up to 2 tiers; each firm is shown once, at its nearest tier.

CompanyChain'21'22'23'24'25YTD
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Talen Energybenef2···+214.8+86.1+2.9
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IonQbenef2·-79.3+259.1+237.1+7.4-4.5
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Quantum Computing Incbenef2-75.8-55.7-39.5+1712.7-38-15.6
D-Wave Quantumbenef2·-85.3-38.9+854.5+211.3-23.2
Nikebenef2+18.7-29-6-29.1-13.8-29.3

YTD as of 2026-07-10 · source: Yahoo Finance

A leading drug-discovery software platform fusing physics-based simulation with machine learning, where subscription software licensing (ACV $198M) is the predictable core and the in-house pipeline is a high-variance upside option. The credibility of 2025's +23% growth comes from large pharma making long-term bets on the platform, as in Novartis's $2.4B multi-target license. Risks are that in-house pipeline trial costs weigh on profit and keep the stock weak, and the compute cost of running large-scale simulation on AWS and NVIDIA GPUs. Upstream on the graph sit AWS (cloud) and NVIDIA (GPU acceleration), and this node is an application demand layer buying compute to sell predictive simulation.

Analysis generated from returns as of 2026-07-09

Analyst ratings

Consensus: Buy 1 · Hold 2 · Sell 0 · Avg. target $17 · Price $16.49 (07-10) · Upside +3%

BrokerRatingTargetPublished
Morgan StanleyEqual-Weight$17May 14, 2026Report
KeyBanc Capital MarketsOverweight$20Apr 8, 2026Report
UBSNeutral$13Mar 17, 2026Report

Morgan Stanley, UBS and KeyBanc all trimmed price targets in H1 2026 on slower software monetization assumptions, though the street consensus remains Buy-tilted.

Analyses covering this node


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